The Rabbit Left Ventricle Modeling at the Cellular Scale: Application to Flow-clamp Experiments

Modeling the cardiac function is often considered using a phenomenological approach, where the cardiac contraction is described macroscopically (at the organ level). However, in this study we use a microscopic approach and describe the rabbit ventricular contraction at the cellular and subcellular levels. This leads to a better description of the ventricle contraction during flow-clamp protocols. Keyword: modeling of physiological systems